Vaccine design platform

Vaccine science, scaled with AI

Velocin designs protein-based vaccines in silico and proves them in the lab. Two decades of parametric systems engineering meet over a decade of protein vaccine science.

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The challenge

Four limitations constrain conventional vaccine development

Slow and expensive manufacturing

Many viral vaccines still rely on decades-old cell-culture production methods that are slow, costly, and difficult to adapt — even to related viruses.

Whole-virus production is infeasible for some viruses

Some viruses, including important enteroviruses, grow poorly in cell culture, making conventional whole-virus vaccine production infeasible.

Immune evasion

Some viruses, including enteroviruses, can divert immune responses toward decoy regions in viral proteins, which can facilitate reinfection.

mRNA vaccines have gaps

Intramuscular mRNA vaccines often induce limited immunity at mucosal surfaces, reducing protection against infection and transmission.

The Velocin answer

Protein-based vaccines designed in silico address all four limitations

Rapid manufacturing and antigen updates

The parametric vaccine design system supports rapid antigen design and updates, while a yield-optimized process manufactures recombinant protein without culturing the target pathogen — at 10–100× the yield of inactivated-virus production.

Applicable across pathogens

We express selected immunogenic regions instead of culturing the target pathogen. The parametric vaccine design system can be redeployed across pathogens, including enteroviruses, influenza viruses, coronaviruses, and Pathogen X.

Targeted immune response

The in silico design engine helps researchers identify regions associated with protection, enabling decoy regions to be excluded from the construct and the immune response to focus on protective targets.

Designed for mucosal protection

Velocin’s protein-based intranasal candidates are designed to induce mucosal immunity, with the goal of reducing infection and transmission in addition to severe disease.

Evidence